#+TITLE: The Sensible Person's Handbook on Drugs #+DATE: <2023-04-22 Sat 07:27> #+BEGIN_EXPORT html #+END_EXPORT * The Sensible Person's Handbook on Drugs ** Introduction this is the introduction hehe ** General Advice on Drug Use *** Be Deliberate ** Harm Prevention - be real, accept not living up to own standards, no denial - the real harm is indirect effects - don't think too much about drugs - don't use drugs to replace actually rewarding activities - don't use drugs as a crutch (two kinds of dependence, chemical and mental) - danger of habits ** Addiction and Dependence *** Homeostatis and Getting Used to It ** Paraphrenelia - scale - vape - time locked box - ginger ** Mechanisms of action *** Neurotransmitters, the Synaptic Cleft, and You *** Agonist *** Antagonist *** Reuptake Inhibitor *** Breakdown Inhibitor *** God is a shitty engineer ** Drug Interactions ** Routes of Administration *** Respiratory System *** Cavities **** Oral **** Nasal **** Anal *** Digestive Tract *** Injecting *** Dermal ** Sourcing *** Research Chemicals *** Dark Web *** Trusted Dealer *** Random People **** Memes ** Drug Effects ** Drug Classes *** Psychedelics *** Stimulants *** Depressants *** Deliriants *** Entactogens *** Weed ** Dosing *** Minimum Viable Drug *** Dose/Response Curves ** Resources ** My Takes on Specific Drugs